September 7, 2024

• Opening Remarks – David Clark
• Family Keynote – Laura Harper
• LEADS & iLEADS Update – Dustin Hammers & Courtney Kloske
• LEADS Q&A and Panel Discussion – Courtney Kloske, Dustin Hammers, Kelly Nudelman, Chiadi Onyike, Angelina Polsinelli, & David Clark
• Get Connected with the Alzheimer’s Association – Greater Indiana Chapter of the Alzheimer’s Association
• Resources Session – Ashley Reiff & Angelina Polsinelli
• Current Therapeutic Updates – Gil Rabinovici
• Current Therapeutic Landscape Discussion – Rebecca Edelmayer, Donna Wilcock, David Clark, & Chiadi Onyike
• What’s Next for LEADS? – Brad Dickerson
• Closing Remarks – Maria Carrillo

January 20-21, 2024

Day One

• Opening Remarks – Brad Dickerson
• Family Keynote – Jenn & Leslie Henry
• Science Keynote:  LEADS Study Overview – Dustin Hammers
• Scientific Session
  • The Importance of Neuropathology – Lea Grinberg
  • Genetics in LEADS – Kelly Nudelman
  • Early Onset Alzheimer’s Disease (EOAD) Signature of Atrophy – Alexandra Touroutoglou
• Medical Resources
  • Speech Pathology Resources – Brielle Stark
  • Neuropsychology & Psychology Resources – Angelina Polsinelli
  • Resources for Enrolling in Clinical Trials – Stephen Hall
• Closing Remarks – Brad Dickerson

Day Two

• Opening Remarks – Maria Carrillo
• Family Keynote – Tony & Kori Gonzales
• Science Keynote:  Emerging Treatments, Challenges & Opportunities – Gil Rabinovici
• Scientific Session
  • Imaging Biomarkers – Renaud La Joie
  • Fluid Biomarkers – Jeff Dage
  • Biomarker Evaluation in Young Onset Dementia in a Diverse Cohort (BEYONDD) – Monica Rivera Mindt
• Community & Advocacy Resources
  • Social Worker Resources – Ashley Reiff
  • Elder Law and Estate Planning Resources – Kerry Peck
  • Lorenzo’s House – Diana Cose
  • Get Connected with the Alzheimer’s Association – Anna Sampley
• Closing Remarks – Maria Carrillo

• Episode 1:  Damage Done
• Episode 2:  Earlier Warning
• Episode 3:  Untimely Intrusion: Early-Onset Alzheimer’s
• Episode 4:  Life in the Real World
• Episode 5:  Halting Progression
• Episode 6:  AD in Black Americans

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• Day One Opening Remarks – Maria Carrillo
• LEADS Study Updates – Liana Apostolova
• Learnings from Imaging, Blood, Cerebrospinal Fluid & Genetics – Gil Rabinovici
• Brain & Behavioral Changes – Brad Dickerson
• Treatment Updates & Perspectives – Liana Apostolova
• Social Workers Resources – Ashley Reiff
• Importance of Neuropathology & Brain Donation – Jessica Tranovich
• Overview of Diagnostics & Biomarkers in LEADS – Jeff Dage & David Clark
• Day One Closing Remarks – Jay Reinstein
• Day Two Opening Remarks – Liana Apostolova
• Day Two Keynote – Joe Montminy
• Communications & Considerations When Communicating with Research Participants – Katie Maslow
• Overview of Medical & Care Resources Following a Diagnosis – Angelina Polsinelli & Lindsey Wineholt
• Day Two Closing Remarks – Maria Carrillo

• Opening Keynote LEADS: Study goals and future directions – Liana G. Apostolova
• Understanding Brain and Behavioral Changes Related to Cognitive Impairment – Including Alzheimer’s, Frontotemporal Dementia, Primary Progressive Aphasia and More – Brad C. Dickerson
• Patient Perspective on the Importance of Receiving an Early Diagnosis – Cindy Weinstein
• Practical Considerations When Living with Early Onset Cognitive Impairment: Conversations with Attorney Pamela Greenfield – Katherine Brandt & Pamela Greenfield
  
• Alzheimer’s Association Panel: Identifying and accessing support groups, other resources, and getting engaged with advocacy – Robert Egge &  Beth Kallmyer
• Understanding Biomarkers – Imaging, Blood, Cerebrospinal Fluid and Genetics – Gil. D. Rabinovici
  
• Panel Session:  Aducanumab Approval and the Dementia Treatment Pipeline: Considerations for Dementia in the Younger Person

• AAIC Study Design & Clinical Characteristics of the LEADS Cohort – Liana G. Apostolova
• Amyloid & Tau PETS in Sporadic Early-Onset Alzheimer’s Disease: Preliminary Results from LEADS – Gil. D. Rabinovici
• MRI Measures of Neurodegeneration in the LEADS Cohort – Brad C. Dickerson
• Examing Early-Onset & Late-Onset Alzheimer’s Disease (EOAD) to Understand the Neuropathological Substract of Typical and Atypical AD – Lea Tenenholz Grinberg