Longitudinal Early-Onset Alzheimer’s Disease Study (LEADS)

The Longitudinal Early-onset AD Study (LEADS) is funded by the National Institute on Aging (NIA) to address several major gaps in Alzheimer’s disease and related dementias research. LEADS is an observational study that will enroll and follow 500 cognitively impaired participants and 100 cognitively normal participants ages 40-64 years at approximately 15 sites in the United States. Clinical, cognitive, imaging, biomarker, and genetic characteristics will be assessed. The primary goal of LEADS is to develop sensitive clinical and biomarker measures for future clinical and research use. Learn More. Join the Fight.