Your ongoing and continued participation is critical to the success of LEADS. Cognitively impaired participants will attend five study visits over four years, and cognitively normal participants will participate for three visits over two years.  Study visits will be split across multiple days.

Study Activities Include

• General medical and neurologic exams
• Cognitive testing
• Biofluid sample collection (blood and spinal fluid samples)
• Neuroimaging (MRI and PET scans)